RNAi tackles a sexually transmitted disease

Article Abstract:

The potential of the process of RNA interference (RNAi) in the prevention and control of herpes simplex virus-2 (HSV-2) in a rodent model is explored. The results reveal that the RNAi in addition to possessing the potential of preventing and controlling viral infections also possesses the advantage of speed that helps in quick translation of the genomic information into effective therapeutics.

HEALTH SERVICES, All Other Miscellaneous Ambulatory Health Care Services, Venereal Disease Prevention, Sexually transmitted diseases, Sexually transmitted disease prevention, Herpesvirus diseases, Herpesvirus infections, Herpes, RNA interference

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An in vitro fluorescence screen to identify antivirals that disrupt hepatitis B virus capsid assembly

Article Abstract:

An in vitro assay of hepatitis B virus (HBV) capsid assembly is developed for testing potential inhibitors, which is based on fluorescence quenching of dye-labeled capsid protein. This approach might facilitate the identification of anitvirals targeting viruses other than HBV, such as avian influenza and HIV.

Product development, Hepatitis B vaccine, Hepatitis B vaccines, Hepatitis B virus

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