Recombining germline-derived CDR sequences for creating diverse single-framework antibody libraries

Article Abstract:

A single-chain Fv antibody library is created which allows complementarity-determining region germline gene fragements to be comined with the variable-region frameworkds HV-DP47 and VL-DPL3.

Sweden, Genetic Engineering

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Novel hydroxycarotenoids with improved antioxidative properties produced by gene combination in Escherichia coli

Article Abstract:

The combination of three carotenoid desaturases with a carotenoid hydratase, a cyclase, and a hydroxylase in Escherichia coli resulted in four new novel carotenoids.

Germany

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A method for the amidation of recombinant peptides expressed as intein fusion proteins in Escherichia coli

Article Abstract:

A modified self-cleaning vacuolar membrane aptase intein expression is used to create mass quantities of amidated peptides.

Scotland, Cellular Biology, Cytology

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