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Engineering receptor-mediated cytotoxicity into human ribonucleases by steric blockade of inhibitor interaction

Article Abstract:

University researchers performed mutation experiments on two human RNases and neurotoxins to increase their toxicity and resistance against cytosolic ribonuclease inhibitor.

Author: Suzuki, Motoshi, Youle, Richard J., Saxena, Shailendra K., Boix, Ester, Prill, Robert J., Vasandani, Veena M., Ladner, Jane E., Sung, Cynthia
Publisher: Nature Publishing Co.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 1999
Research and Testing Services, Scientific Research and Development Services, Genetic Engineering, Research & Development-Universities, Brief Article, University research

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Viral vectors do the DNA shuffle

Article Abstract:

Researchers at the University of California, San Diego have used retroviruses to transfer genetic material into cells.

Author: Miyanohara, Atsuhi, Friedmann, Theodore
Publisher: Nature Publishing Co.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2000
California, Cellular Biology, Cytology

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