There once was a tick from Lyme..

Article Abstract:

SmithKline Beecham has developed a vaccine, LYMErix, against spinochete, that causes Lyme disease, which has been unnanimously recommended for approval by a USDA advisory panel. Hastily following SmithKline, Swiftwater, PA-based Pasteur Merieux Connaught plans to submit the results of clinical trials on a like vaccine. Long-term efficacy has not been established for either company's drug, but the initial results of tests are promising.

Comment:

Plans to submit the results of clinical trials on a like vaccine

Product introduction, SmithKline Beecham Corp. (Philadelphia, Pennsylvania), Article, Pasteur Merieux Connaught

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Simple recipe for blocking ion channels

Article Abstract:

A simple and elegant recipe for producing specific inhibitory polyclonal antibodies that could be targeted to any ion channel with a six-transmembrane-domain structure is presented. Such antibodies would facilitate the study of excitable cells and, as many of these channels are potential drug targets, might provide a starting point for the development of therapeutic antibodies.

Science & research, Polyclonal Antibodies, Research, Membrane proteins

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Vaccines to die for

Article Abstract:

"Naked" DNA vectors are relatively easy to engineer and produce. They have the advantage over vaccines based on recombinant viruses in that they do not need to be covered with proteins or lipids.

Product development

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