TnAraOut, A transposon-based approach to identify and characterize essential bacterial genes

Article Abstract:

The validation of new antibacterial drug targets is seeing a new approach with a high potential. The new approach, called TnAraOut, involves the identification of genes that encode essential bacterial genes.

Author: Judson, Nicholas, Mekalanos, John J.
Genetic Engineering

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AAV muscles ahead

Article Abstract:

Scientists from the Stanford University and ARIAD Pharmaceuticals compared adeno-associated viral (AAV) and adenoviral vectors and used both to transfect muscle cells of mice using a rapamycin-inducible gene expression system. The AAV vector was shown to be more stable in human growth hormone synthesis.

ARIAD Pharmaceuticals Inc., ARIA

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Subjects list: United States, Viral research
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