Cold-denatured ensemble of apomyoglobin: implications for the early steps of folding

Article Abstract:

Various spectroscopies were used to study the cold-denatured equine apomyoglobin in aqueous solutions at temperatures between -20 to 98 degrees Centigrade. The cold denaturation of apomyoglobin was found to be different from acid-induced folding in many aspects and can be well described by a cooperative transition below 3 degrees Centigrade. Moreover, an examination of the N-terminal A-peptide fragment of equine apomyoglobin in aqueous and trifluoroethanol solutions revealed that cold denaturation leads to the breakdown of the AGH-hydrophobic interface.

Proteins, Myoglobin, Protein denaturation

---

Hydrophobic effects on a molecular scale

Article Abstract:

Research was conducted to examine hydrophobic hydration and interactions on a molecular scale and the effects of pressure, temperature and salt concentration on them using a new theoretical approach. The objective is to improve the understanding of the molecular origins of hydrophobic effects. Results confirm that the basic information theory model provides a simple theoretical framework to study many hydrophobic phenomena on a molecular scale since it has already led to a new understanding of the temperature dependence of hydrophobic hydration.

Hydration, Rehydration solutions, Micelles, Molecules, Perturbation (Quantum dynamics), Perturbation (Mathematics)

---

Similar abstracts:

• Abstracts: Gaussian model for localized translational motion: Application to incoherent neutron scattering. Inelastic neutron scattering studies of the interaction between water and some amino acids
• Abstracts: Calculations of band gaps in polyaniline from theoretical studies of oligomers. Dynamic and static light scattering and fluorescence studies of the interactions between lactate dehydrogenase and poly(ethyleneimine)
• Abstracts: Comment on "A study of mechano-catalysis for overall water splitting". Solubility of methane in water: The significance of the methane-water interaction potential
• Abstracts: All-atom empirical potential for molecular modeling and dynamics studies of proteins. Influence of solid solution formation on polarity: Molecular modeling investigation of the system 4-chloro-4'-nitrostilbene/4,4'-dinitrostilbene
• Abstracts: A density functional theory study of the hydrates of NH3.H2SO4 and its implications for the formation of new atmospheric particles

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.