Defects can increase the melting temperature of DNA-nanoparticles assemblies

Article Abstract:

DNA-gold nanoparticle assemblies can be used as an alternative technology to DNA microarrays for DNA detection and RNA profiling. The results have demonstrated that the surface-bound DNA display hybridization behavior different from that of free DNA, indicating that a detailed understanding of DNA-nanoparticle assembly phase behavior is required for quantitative interpretation of DNA-nanoparticle aggregation.

Author: Harris, Nolan C., Ching-Hwa Kiang
Publisher: American Chemical Society
Publication Name: Journal of Physical Chemistry B
Subject: Chemicals, plastics and rubber industries
ISSN: 1520-6106
Year: 2006
Thermal properties, Chemical properties, DNA microarrays, Nanoparticles

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"One-into-many" model: An approach on DFT based reactivity descriptor to predict the regioselectivity of large systems

Article Abstract:

A model is developed to predict the regioselectivity of large chemical and biological systems. A large system, right-handed B-DNA is broken into small fragments in this model and then the local reactivity of the concerned atomic sites in the individual fragments are evaluated on the basis of DFT.

Author: Saha, Soumen, Roy, Ram Kinkar
Publisher: American Chemical Society
Publication Name: Journal of Physical Chemistry B
Subject: Chemicals, plastics and rubber industries
ISSN: 1520-6106
Year: 2007
Models, Density functionals, Density functional theory, Biological systems

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Subjects list: Research, Analysis, DNA
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