Evidence for the "cold fusion" of bilayer membranes

Article Abstract:

Research was conducted to examine the hypothesis that the polymerization of the lipid headgroups inhibits calcium-induced fusion of small unilamellar vesicles of the lipid di-n-dodecyloxypropyl beta-nitrostyryl phosphate but does not affect vesicle aggregation. A comparison of titrations of vesicles into CaCl2 in the absence and presence of LMPAM provided an accurate microcalorimetric determination of the enthalpies of vesicle aggregation and fusion. Results reveal that the driving force of membrane fusion is of entropic origin.

Research, Membrane fusion, Cold fusion, Lipid membranes, Bilayer lipid membranes

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pH-dependent phase behavior of carbohydrate-based gemini surfactants. Effect of the length of the hydrophobic spacer

Article Abstract:

A study on the phase behavior of a series of carbohydrate-based gemini surfactants with varying spacer lengths is conducted using static and dynamic light scattering between pH 2 and 12. Upon increasing the pH to slightly basic values, flocculation followed by redispersion upon charge reversal is observed up to a spacer length of eight methylene units.

Pharmaceutical Preparation Manufacturing, Pharmaceutical preparations, Carbohydrates, Light scattering

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Phase behavior of amphiphilic lipid molecules at air-water interfaces: an off-lattice self-consistent-field modeling

Article Abstract:

Off-lattice self-consistent-field theory is used to study the phase behavior of both saturated and unsaturated lipid molecules at air-water interfaces. In saturated lipids, the micellar and lamellar phases show first-order phase transitions, which are sensitive to the hydrophilicity and hydrophobicity of lipid molecules.

Lipids, Crystal lattices

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