Use of the matrix form of the fundamental equations for transformed Gibbs energies of biochemical reaction systems at three levels

Article Abstract:

Issues concerning biochemical reaction thermodynamics using Gibbs energy equations at three levels are presented.

Author: Alberty, Robert A.
Measurement, Adenosine triphosphate, ATP, Chemistry, Organic, Organic chemistry, Adenosine diphosphate, Gibbs' equation

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Calculation of equilibrium compositions of large systems of biochemical reactions

Article Abstract:

The benefits of choosing coenzymes as elements in considering the thermodynamics of systems of biochemical reactions in a living cell where the concentrations of coenzymes are in steady states are discussed. When the concentrations of coenzymes are constant, their conservation equations are eliminated.

Author: Alberty, Robert A.
Biochemistry, Coenzymes

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Effect of pH on protein-ligand equilibria

Article Abstract:

The dependence of K' on pH to provide information on the acid dissociation constants of acid groups in the binding site of the protein before and after binding a ligand is studied and provided. The pH dependencies of the standard transformed Gibbs energy of formation of the catalytic site in fumarase and for the site occupied by succinate and the three isomers of tartrate are calculated.

Author: Alberty, Robert A.
Science & research, Proteins, Ligands, Ligands (Chemistry), Hydrogen-ion concentration, Chemical properties, pH

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Subjects list: Research, Chemistry, Physical and theoretical, Physical chemistry, Thermodynamics
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