Abstracts

Chemistry

Search abstracts:

Streptogramins, oxazolidinones, and other inhibitors of bacterial protein synthesis

Article Abstract:

The structure, mode of action, and resistance to the streptogramin and oxazolidinone antibiotics- two distinct classes of antibiotics that have recently brought to market for treatment of bacterial infections- are described and also, a brief discussion of some new and old classes of antibiotics that block translation is presented. Streptogramin antibiotics are natural products produced by various members of the Streptomyces genus.

Protein synthesis, Protein biosynthesis

---

Rifamycin-mode of action, resistance, and biosynthesis

Article Abstract:

Rifamycin belongs to the family of ansamycin antibiotics and it displays a broad spectrum of antibiotic activity against Gram-positive and, to a lesser extent, Gram-negative bacteria and different prokaryotic organisms show different degrees of susceptibility to inhibition by rifamycins. The inhibition of DNA-dependent RNA polymerase seems to be the common mechanism for all antibacterially active rifamycins.ll

---

Bacterial topoisomerase inhibitors: Quinolone and pyridone antibacterial agents

Article Abstract:

The quinolone anti-infective agents are of wholly synthetic origin and a wide variety of clinical indications are approved for quinolones including many infections commonly encountered in community-like gastrointestinal infections, respiratory infections and gynecologic infections. The availability of nalidixic acid was instrumental in assisting the discovery of the targeted bacterial type II topoisomerases.

Quinolones

Similar abstracts:

• Abstracts: Syntheses of gem-dihalocyclopropanes and their use in organic synthesis. Thioamides as useful synthons in the synthesis of heterocycles
• Abstracts: Syntheses of gem-dihalocyclopropanes and their use in organic synthesis. part 2 Cycloproparenes
• Abstracts: Salt effects resulting from exchange between two ion pairs and their crucial role in reaction pathways. Binary vanadium chalcogenide complexes
• Abstracts: Measurements of peroxides and what they tell us. Fluorinated peroxides. Singlet-oxygen chemiluminescence in peroxide reactions
• Abstracts: Synthetic analogues of cysteinate-ligated non-heme iron and non-corrinoid cobalt enzymes. Synthetic analogues of the active sites of iron-sulfur proteins

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.