Total synthesis of oxyacyclic macrodiolide natural products
Article Abstract:
Total syntheses of macrodiolides containing oxyacyclic rings, which exhibit many different bioactivities, was discussed and described. Various macrodiolides like pamamycin, amphidinolide, swinholide, glucolipsin A, tartrolon B, cyclic hemiketal and cyclic acetal macrodiolides were synthesized and studied.
Publication Name: Chemical Reviews
Subject: Chemistry
ISSN: 0009-2665
Year: 2005
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Total synthesis of alpha-pyrone meroterpenoids, novel bioactive microbial metabolites
Article Abstract:
The total synthesis of acyl-CoA/cholesterol acyltransferase (ACAT)-inhibiting alpha-pyrone meroterpenoids, designated as pyripyropenes and acetylcholinesterase (AChE)- inhibiting arisugacins is described. A collection of microorganisms is screened for metabolites that selectively inhibit ACAT and AChE.
Publication Name: Chemical Reviews
Subject: Chemistry
ISSN: 0009-2665
Year: 2005
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Total synthesis of selected bioactive natural products: Illustration of strategy and design
Article Abstract:
The total synthesis of selected bioactive natural products is described. The dynamic as well as elegant parts of the total synthetic procedure of practically useful bioactive compounds are described.
Publication Name: Chemical Reviews
Subject: Chemistry
ISSN: 0009-2665
Year: 2005
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