gem-Disubstituent effect: Theoretical basis and synthetic applications
Article Abstract:
The biological implications for the gem-disubstitution in the mechanism of enzymatic catalysis and the numerous applications in the design of new pharmaceutical are described. The conclusions state that the origin of the gem-disubstituent effect might vary depending on the system being analyzed.
Publication Name: Chemical Reviews
Subject: Chemistry
ISSN: 0009-2665
Year: 2005
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Synthetic methods for azaheterocyclic phosphonates and their biological activity
Article Abstract:
Amino phosphonates and aminophosphonic acids are the topics of interest for a variety of socially relevant fields like medicinal, pharmaceuticals, agrochemical and biochemical. Various subdivision and classification of these compound based on the reaction which it undergoes is detailed.
Publication Name: Chemical Reviews
Subject: Chemistry
ISSN: 0009-2665
Year: 2004
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Human pharmaceuticals in the aquatic environment: A challenge to green chemistry
Article Abstract:
The background of pharmaceuticals in the environment problems and uncertainties are discussed. Focus is laid on pharmaceuticals used in human medicine, some of which are also applied in veterinary medicine.
Publication Name: Chemical Reviews
Subject: Chemistry
ISSN: 0009-2665
Year: 2007
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