A short-term trial of tacrolimus ointment for atopic dermatitis

Article Abstract:

The immunosuppressant drug tacrolimus may be effective in the treatment of atopic dermatitis. This skin disorder is characterized by dry, itchy, inflamed skin. Researchers randomly assigned 215 patients with atopic dermatitis to apply a placebo or one of three different dosages of tacrolimus to their skin. All three dosages significantly reduced symptoms when compared to the placebo. A burning sensation at the site of application was the only adverse effect of tacrolimus. There was no significant advantage of one dosage over another.

Author: Ruzicka, Thomas, Bos, Jan D., Schopf, Erwin, Bieber, Thomas, Rubins, Andris, Dobozy, Attila, Jablonska, Stefania, Ahmed, Imitiaz, Thestrup-Pedersen, Kristian, Daniel, Francois, Finzi, Aldo, Reitamo, Sakari
Evaluation, Immunosuppressive agents

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Atopic dermatitis

Article Abstract:

A case study of a 10-year old girl with atopic dermatitis is reported with itching sensation that has become relentless, resulting in sleep loss. The differential diagnosis treatment of atopic dermatitis is presented also giving the therapeutic interventions for the same that include topical cortico-steroids, topical doxepin and oral corticosteroid.

Author: Williams, Hywel C.
Case studies, Diagnosis, Doxepin

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Long-term outcomes after repeat doses of antenatal corticosteroids

Article Abstract:

The effects of the long-term usage of single and repeat courses of antenatal corticosteroids on children are examined. The courses are found to improve several neonatal outcomes in infants, though they increase the risk of intrauterine growth restriction.

Author: Peaceman, Alan M., Leveno, Kenneth J., Caritis, Steve N., Mercer, Brian, Gabbe, Steven G., Sorokin, Yoram, Rouse, Dwight J., Wapner, Ronald J., Spong, Catherine Y., Carpenter, Marshall W., Thorp, John M., Mele, Lisa, Dudley, Donald J., Harper, Margaret, Ramin, Susan, Johnson, Francee, Malone, Fergal
Science & research, Research, Prevention, Complications and side effects, Physiological aspects, Infants (Newborn), Neonatal diseases, Prenatal influences, Clinical report

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Subjects list: Drug therapy, Atopic dermatitis, United Kingdom, Usage, Corticosteroids, Corticosteroid drugs
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