AAVant-garde gene therapy
The authors discuss how the use of adeno-associated virus (AAV) to deliver canine factor IX gene in dogs was able to partially correct hemophilia B. Although they do not see this process readily converted to use in humans, they think it will be useful for research in gene therapy.
Publication Name: Nature Medicine
Advances in the understanding and treatment of acromegaly are discussed. It is believed that understanding the development, function, and regulation of somatotroph cells provides insights into the cellular origin of this tumor as well as approaches to the treatment of acromegaly.
Publication Name: The New England Journal of Medicine
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