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Anti-inflammatory actions of lipoxin A4 and asprin-triggered lipoxin are SOCS-2 dependent

Article Abstract:

Lipoxins and aspirin-triggered lipoxins are crucial modulators of proinflammatory responses. Lipoxins activate two receptors in dendritic cells, AhR and lipoxin A4 receptor, and that this activation triggers expression of suppressor of cytokine signaling (SOCS)-2.

Author: Serhan, Charles N., Machado, Fabiana S., Johndrow, James E., Esper, Lisia, Dias, Alexandra, Bafica, Andre, Aliberti, Julio
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2006
Science & research, Pharmaceutical Preparation Manufacturing, Pharmaceutical preparations, Aspirin, Aspirin Combinations, Research, Cytokines, Dendritic cells

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A radically twisted lipid regulates vascular death

Article Abstract:

Lipids and free radicals regulate retinal vascular stability through regulation of antiangiogenic proteins. Stabilization of the vascular network might help in preventing new blood vessel growth and blindness.

Author: Smith, Lois E.H., Connor, Kip M.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2005
All Other Miscellaneous Chemical Product and Preparation Manufacturing, Chemical preparations, not elsewhere classified, Free Radicals, Risk factors, Neovascularization, Free radicals (Chemistry), Retrolental fibroplasia, Retinopathy of prematurity

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Subjects list: Health aspects, United States
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