Association between risk factors for coronary heart disease in schoolboys and adult mortality rates in the same localities
Certain factors increase the risk of developing coronary heart disease, which affects the coronary arteries, the major blood vessels supplying the heart. The risk factors for coronary heart disease were assessed in 15- to 16-year-old boys from two schools, located in areas with a fourfold difference in death rate from adulthood coronary heart disease. One school was situated in an underprivileged urban community with a high prevalence of coronary heart disease, and was considered high-risk. The other school was located in an semi-rural, affluent community with an average incidence of coronary heart disease, and was considered low-risk. Risk factors such as smoking, high blood pressure, high blood cholesterol, obesity, physical fitness, and inactivity, were assessed. There was a higher prevalence of smoking, increased body fat, poor diet, and physical inactivity among boys from the high-risk area as compared with boys from the low-risk community. Blood lipid levels, maximum oxygen uptake, and incidence of high blood pressure were similar for both groups. Results confirm that risk factors for coronary heart disease are related to death rates. Health education to prevent smoking, improve diet, and increase activity should be provided to school children, particularly those from areas with a high death rate due to coronary heart disease. (Consumer Summary produced by Reliance Medical Information, Inc.)
Publication Name: Archives of Disease in Childhood
Weight-independent cardiovascular fitness and coronary risk factors
Children with high levels of body fat may have a high risk for developing coronary artery disease (CAD) and diabetes, regardless of their level of fitness. Researchers evaluated 74 children for levels of body fat, cardiovascular fitness, blood pressure, triglycerides, cholesterol, insulin, glucose, and glycohemoglobin. Children with higher levels of fat were much more likely to have high systolic blood pressure, triglycerides, and cholesterol. Cardiovascular fitness was not associated with blood levels. Since an unfavorable risk profile for heart disease may begin in childhood, children should be encouraged to exercise and eat a healthy diet.
Publication Name: Archives of Pediatrics & Adolescent Medicine
Relative importance of various risk factors for asymptomatic carotid atherosclerosis versus coronary heart disease incidence
The study examined the major risk factors for coronary heart disease and early carotid artery thickening to determine a pattern or whether they differed for the two outcomes. High triglyceride-low HDL cholesterol patterns appear to be involved in the transitions from atheroma to atherothrombosis. The study examined 12, 193 participants.
Publication Name: American Journal of Epidemiology
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