Calcium-channel blockers for hypertension - uncertainty continues

Article Abstract:

Research published in 1998 indicated that calcium-channel blockers, a class of drugs used to lower blood pressure, may raise the risk of heart attack in some patients. Drugs of this class, in clinical use for almost 20 years, have been the most-prescribed medications for high blood pressure. Other research studies, some better designed to assess the risk of heart attack, may more firmly establish the relative safety of calcium-channel blockers. National guidelines for hypertension management recommend beta-blockers and diuretic drugs as the first choices to control blood pressure.

Editorial, Complications and side effects, Risk factors, Heart attack, Calcium channel blockers

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Angiotensin receptors and their antagonists

Article Abstract:

Angiotensin receptor blockers are a new class of drug that may prove as beneficial as ACE inhibitors. Angiotensin receptor blockers prevent angiotensin II from binding to its receptor. Angiotensin II receptors are located in many organs such as blood vessels, heart, kidneys and brain. Angiotensin receptor blockers appear to be as effective in reducing high blood pressure as ACE inhibitors and without the side effects typical of ACE inhibitors, such as cough and angioedema. They are also effective in the treatment of heart failure.

Heart failure, Angiotensin, Angiotensin receptors

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Carvedilol. (Review Article)

Article Abstract:

The drug carvedilol has proven benefits in treating congestive heart failure, hypertension and coronary artery disease. This drug is a beta blocker but it also inhibits the alpha1 adrenoreceptor. It works primarily by dilating blood vessels. Common side effects include tissue swelling, dizziness, low blood pressure, slow heartbeat, nausea, diarrhea, and blurred vision. It can also damage the liver and should not be used in patients with liver disease.

Analysis, Coronary heart disease, Congestive heart failure, Congestive heart failure agents, Adrenergic beta blockers, Adrenergic beta-antagonists

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