Calcium plus vitamin D supplementation and risk of colorectal cancer

Article Abstract:

Randomized-trial evidence that calcium with vitamin D supplementation is beneficial in the primary prevention of colorectal cancer is examined. Daily supplementation of calcium with vitamin D for seven years had no effect on the incidence of colorectal cancer among postmenopausal women, and the long latency associated with the development of colorectal cancer, along with seven year duration of trial may have contributed to this null finding.

Author: Ockene, Judith K., Caan, Bette, Robbins, John, Hendrix, Susan L., Wallace, Robert B., Hays, Jennifer, Heiss, Gerardo, Hsia, Judith, Howard, Barbara V., Black, Henry R., Brzyski, Robert G., Assaf, Annlouise R., Wactawski-Wende, Jean, Gass, Margery, Anderson, Garnet L., Brunner, Robert, Sarto, Gloria E., Phillips, Lawrence, Chelbowski, Rowan T., Hubell, Allan, Kotchen Jane Morley, OSullivan, Mary Jo, Margolis, Karen l., Pottern, Linda, Prentice, Roll L., Rohan , Thomas E., Sharma, Santosh, Srefanick, Marcia L., Horn, Linda Van, Whitlock, Evelyn, Bassword, Tmasen, Beresword, Shirley A.A., Bonds, Densie E., Cochrane, Barbara V., Garland, Cedric
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2006
Pharmaceutical Preparation Manufacturing, All Other Basic Inorganic Chemical Manufacturing, Pharmaceutical preparations, England, Industrial inorganic chemicals, not elsewhere classified, Calcium, Calcium Supplements, Prevention, Colorectal cancer, Dosage and administration, Vitamin D, Calcium (Nutrient), Calcium, Dietary, Alfacalcidol, Calcifediol

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Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women: a randomized controlled trial

Article Abstract:

Postmenopausal women who take hormone replacement therapy may have twice the risk of developing dementia compared to other postmenopausal women, according to a study of 4,532 women. Hormone replacement therapy did not prevent mild intellectual deficits either. This study is part of the Women's Health Initiative study, which found that hormone replacement therapy may do more harm than good.

Author: Ockene, Judith K., Shumaker, Sally A., Hendrix, Susan L., Wallace, Robert B., Rapp, Stephen R., Wassertheil-Smoller, Sylvia, Jackson, Rebecca D., Legault, Claudine, Thal, Leon, Jones, Beverly N., III, Assaf, Annlouise R., Kotchen, Jane Morley, Wactawski-Wende, Jean
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2003
Complications and side effects, Risk factors, Dementia, Hormone therapy, Alzheimer's disease, Hormone replacement therapy

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Conjugated equine estrogens and incidence of probable dementia and mild cognitive impairment in postmenopausal women

Article Abstract:

The effects of conjugated equine estrogens (CEE) alone and CEE plus medroxyprogesterone acetate (MPA) on incidence of portable dementia and mild cognitive impairment (MCI) in older women are determined. It was observed that estrogen therapy alone did not reduce dementia or MCI incidence and increased the risk.

Author: Coker, Laura H., Shumaker, Sally A., Hendrix, Susan L., Kuller, Lewis, Masaki, Kamal, Rapp, Stephen R., Stefanick, Marcia L., Legault, Claudine, Thal, Leon, Lane, Dorothy S., Lewis, Cora E., Fillit, Howard
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2004
United States, Science & research, Health aspects, Research, Postmenopausal women, Medroxyprogesterone, Conjugated estrogens

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