Can HIV-1-contaminated syringes be disinfected?: implications for transmission among injection drug users

Article Abstract:

Disinfection of HIV-1-contaminated syringes and implications for transmission among injection drug users (IDUs) are discussed. Bleach (sodium hypochlorite) was found in a laboratory study study designed to replicate injection behaviors to be highly effective in reducing the viability of HIV-1 even after minimal contact time. The HIV-1 recovery was not reduced to zero. Three washes with water was found to be almost as effective as a single rinse with undiluted bleach in cutting likelihood that contaminated syringes harbor viable HIV-1. IDUs do share syringes and should be encouraged to clean them, preferably with undiluted bleach.

Author: Abdala, Nadia, Gleghorn, Alice A., Carney, John M., Heimer, Robert
United States, Research, Usage, Prevention, Behavior, Disease transmission, Drug delivery systems, Water, Drug addicts, Drug abusers, Drug abuse, AIDS (Disease), Disinfectants, Syringes, Chlorine, Chlorine and derivatives as disinfectants, Bleaching materials, Bleaches, Chlorine compounds

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The Effect of acids on the survival of HIV during drug injection

Article Abstract:

Data from ethnographic studies of injection drug use practices are combined with laboratory virology to evaluate the effects of exposure to acids during drug preparation and injection on HIV-I viability. Results indicate that short exposure reduced recovery of viable HIV-1but did not totally eliminate infectious HIV-1.

Author: Abdala, Nadia, Heimer, Robert, Kinzly, Mark L., He, Helen
All Other Basic Organic Chemical Manufacturing, Industrial organic chemicals, not elsewhere classified, Citric Acid, Drug therapy, Clinical report

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HIV-1 transmission in injection paraphernalia: heating drug solutions may inactivate HIV-1

Article Abstract:

Heating drugs to at least 150 degrees F. for 15 seconds or longer may inactivate HIV. Many drug addicts heat their drugs before injecting them in a device called a cooker.

Author: Abdala, Nadia, Heimer, Robert, Sotheran, Jo L., Clatts, Michael C., Goldsamt, Lloyd A., Anderson, Kenneth T., Gallo, Toni M., Hoffer, Lee D., Luciano, Pellegrino A., Kyriakides, Tassos
Drugs, HIV (Viruses), HIV, Production processes, Virus inactivation

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Subjects list: Health aspects, HIV infection, HIV infections
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