Changes in estrogen receptor messenger ribonucleic acid in sheep fetal and maternal tissues during late gestation and labor
Article Abstract:
Estrogen receptor messenger RNA (mRNA) appears to increase during labor in the uterus and cervix of pregnant sheep. This supports the theory that estrogen plays a role in labor. Pregnant ewes had tissue samples periodically taken under general anesthesia beginning in the last third of pregnancy. Tissue samples were analyzed for estrogen receptor mRNA. Some ewes were allowed to go into labor spontaneously; others had labor induced by an intravenous infusion of cortisol. Some lambs had their adrenal glands removed to examine the effect of fetal adrenal hormones on estrogen receptor mRNA production. Estrogen receptor mRNA increased in uterine muscle cells, uterine lining cells, and the cervix around the time of labor but was not found in the placenta, fetal membranes, or broad uterine ligament. This occurred whether labor was spontaneous or induced. Removing fetal adrenal glands caused a profound decrease in estrogen receptor mRNA.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1995
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Electrocortical and heart rate response during vibroacoustic stimulation in fetal sheep
Article Abstract:
Vibration and sound stimulation appear to produce reliable brain wave and heart rate patterns in fetal sheep. Heart rate and brain wave patterns were measured during vibration and sound stimulation in eight near-term sheep fetuses previously implanted with electrodes. Fetal heart rates decreased significantly during quiet sleep and increased slightly during active sleep when stimulated. Stimulation resulted in a decrease in lower frequency brain waves during quiet sleep and an increase in higher frequency brain waves during active sleep.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1997
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Betamethasone effects on ovine uterine and umbilical placental perfusion at the dose used to enhance fetal lung maturation
Article Abstract:
A study to examine the glucocorticoid effect of the umbilical placental perfusion was conducted. The results revealed that fectoplacental perfusion during the glucocorticoid exposure is not limiting for exchange of nutrition.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2006
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