Reproductive Period and Risk of Dementia in Postmenopausal Women

Article Abstract:

A longer reproductive period that exposes women to estrogen for longer periods of time does not reduce the risk of dementia or Alzheimer's disease. This was the conclusion of a study of 3,601 postmenopausal women who were followed for up to 10 years.

Author: Hofman, Albert, Geerlings, Mirjam I., Ruitenberg, Annemieke, Witteman, Jacqueline C. M., van Swieten, John C., van Duijn, Cornelia M., Breteler, Monique M. B., Launer, Lenore J.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2001
Dementia, Estrogen, Estrogens

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Nonsteroidal antiinflammatory drugs and the risk of Alzheimer's disease

Article Abstract:

The long-term use of non-steroidal anti-inflammatory drugs (NSAIDs) may reduce the risk of Alzheimer's disease, according to a study of 6,989 people. However, it does not appear to reduce the risk of other types of dementia, particularly vascular dementia.

Author: Hofman, Albert, Ruitenberg, Annemieke, Launer, Lenore J., Veld, Bas A. in 't, Duijn, Cornelia M., Stijnen, Theo, Breteler, Monique M.B., Stricker, Bruno H.C.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2001
Prevention, Nonsteroidal anti-inflammatory drugs, Nonsteroidal anti-inflammatory agents

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Complement factor H polymorphism, complement activators and risk of age-related macular degeneration

Article Abstract:

An objective of assessing the associations between the complement factor H gene and age related macular degeneration (AMD) in the general population is undertaken. Results of a study conducted indicate that the complementary factor H, an inhibitory gene of the complement pathway is a major risk factor for AMD in this population.

Author: Hofman, Albert, Witteman, Jacqueline C.M., van Duijn, Cornelia M., Stijnen, Theo, Vingerling, Johannes R., Klaver, Caroline C.W., Despriet, Dominiek D.G., Bergen, Arthur A.B., Kardys, Isabella, De Maat, Moniek P.M., Boekhoorn, Sharmila S., Oostra, Ben A., Uitterlinder, Andre G.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2006
Genetic aspects, Macular degeneration, Disease/Disorder overview

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Subjects list: Health aspects, Risk factors, Alzheimer's disease
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