Discontinuation of secondary prophylaxis against Pneumocystis carinii pneumonia in patients with HIV infection who have a response to antiretroviral therapy
HIV patients whose CD4 T cell counts increase to 200 or more in response to antiretroviral therapy can stop taking drugs to prevent Pneumocystis carinii pneumonia (PCP). In a study of 325 such patients, none developed PCP during an average of 13 months after they stopped taking drugs to prevent PCP.
Publication Name: The New England Journal of Medicine
Regional differences in use of antiretroviral agents and primary prophylaxis in 3,122 European HIV-infected patients
This study points out that once clinical trials are finished, actual use of drugs designed to protect HIV-infected patients from opportunistic infections may vary widely. It was learned that this is the case across Europe, and guidelines have not been followed.
Publication Name: Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology
HIV Viral Load Response to Antiretroviral Therapy According to the Baseline CD4 Cell Count and Viral Load. (Original Contribution)
HIV patients whose CD4 T cell counts are less than 200 may still respond to highly active antiretroviral therapy (HAART), according to a study 3,226 patients. This was true even in patients who had large amounts of virus in their blood.
Publication Name: JAMA, The Journal of the American Medical Association
- Abstracts: Aerosol pentamidine for secondary prophylaxis of AIDS-related Pneumocystis carinii pneumonia: a randomized, placebo-controlled study
- Abstracts: Aerosol pentamidine for secondary prophylaxis of AIDS-related Pneumocystis carinii pneumonia: a randomized, placebo-controlled study. part 2
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