Effect of a single mass antibiotic distribution on the prevalence of infectious trachoma

Article Abstract:

A study was conducted to determine whether ocular chlamydial infection returns to the community up to 24 months after a single mass antibiotic distribution in a hypernedemic region of Ethiopia. The findings showed that ocular chlamydial infection was not eliminated in children aged 1 to 5 years after a single mass azithromycin distribution, slowly returning over 24 months and repeated treatments or other effective measures would be necessary for elimination.

Author: Melese, Muluken, Cevallos, Vicky, Gaynor, Bruce D., Whitcher, John P., Lietman, Thomas M., Chidambaram, Jaya D., Alemaychu, Wondu, Lakew, Takele, Elizabeth, Yi, House, Jenafir, Zhaoxia Zhou, Maxey, Kathryn, Shapiro, Brett L., Lee, C. David, Srinivasan, Muthiah, Porco, Travis
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2006
Ethiopia, Children, Development and progression

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Feasibility of eliminating ocular chlamydia trachomatis with repeat mass antibiotic treatments

Article Abstract:

The rate at which chlamydial infection returns to a population after mass treatment is determined and the treatment frequency required for elimination of ocular chlamydia form a community is estimated. The result indicates that elimination of infection in a hyperendynamic area is feasible with biannual mass antibiotic administrations and attainable coverage levels.

Author: Melese, Muluken, Chidambaram, Jaya Devi, Alemayehu, Wondu, Lee, David Chung, Cevallos, Vicky, Zhou, Zhaoxia, Donnellan, Cathy, Saidel, Michael, Yi, Elizabeth H., Gaynor, Bruce D., Whitcher, John P., Lietman, Thomas M.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2004
Science & research, Research, Drug therapy

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Comparison of annual and biannual mass antibiotic administration for elimination of infectious trachoma

Article Abstract:

A study to confirm if administration of biannual treatment can help eliminate ocular chlamydial infection in preschool children and compared the results with the World Health Organization recommendations for annual treatment is conducted. Results prove that administration of antibiotics biannually could eliminate ocular chlamydial infection.

Author: Porco, Travis C., Melese, Muluken, Alemayehu, Wondu, Cevallos, Vicky, Gaynor, Bruce D., Whitcher, John P., Lietman, Thomas M., Chidambaram, Jaya D., Lakew, Takele, House, Jenafir, Zhaoxia Zhou, Yi, Elizabeth, Ray, Kathryn, Hong, Kevin Cyrus, Phan, Isabella, Zaidi, Ali
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2008
United States, Product standards, safety, & recalls, Standards, Patient outcomes, Diagnosis, Antibiotics, Control, Dosage and administration, Preschool children, World Health Organization, Clinical report

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Subjects list: Health aspects, Care and treatment, Chlamydia infections
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