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Effect of magnesium sulfate given for neuroprotection before preterm birth: a randomized controlled trial

Article Abstract:

Magnesium sulfate given intravenously during labor may benefit premature babies, according to a study of 1047 pregnant women who delivered prematurely. Babies whose mothers received intravenous magnesium sulfate had fewer disabilities at age two than babies whose mothers did not receive magnesium sulfate. Magnesium sulfate had no serious side effects.

Author: Doyle, Lex W., Crowther, Caroline A., Hiller, Janet E., Haslam, Ross R.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2003
All Other Basic Inorganic Chemical Manufacturing, Industrial inorganic chemicals, not elsewhere classified, Magnesium Sulfate, Care and treatment, Evaluation, Cerebral palsy, Premature labor, Premature labour

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Outcomes at 2 years of age after repeat doses of antenatal corticosteroids

Article Abstract:

A randomized and controlled study to analyze the long-term effects of repeat doses of antenatal corticosteroids in children is conducted. The results show that the drug reduces the neonatal morbidity without changing the neurosensory disability or body size of two-year-old children.

Author: Harding, Jane E., Doyle, Lex W., Crowther, Caroline A., Hiller, Janet E., Haslam, Ross R., Robinson, Jeffery S.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2007
United Kingdom, Science & research, Research, Usage, Complications and side effects, Physiological aspects, Infants (Newborn), Neonatal diseases, Prenatal influences, Clinical report

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Neonatal adrenal function after repeat dose prenatal corticosteroids: A randomized controlled trial

Article Abstract:

A study was conducted with the objective to find out if repeated prenatal corticosteroids suppress neonatal cortisol concentrations. It was concluded that the short-or-long-term clinical impact, if any, of the changes in adrenal function needs to be determined.

Author: Crowther, Caroline A., Hiller, Janet E., Haslam, Ross R., Robinson, Jeffrey S., Ashwood, Patricia J., Willson, Kristyn J., Kennaway, David J.
Publisher: Elsevier B.V.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2006
United States, Causes of, Risk factors, Birth defects, Addison's disease

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Subjects list: Prevention, Corticosteroids, Corticosteroid drugs
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