Emerging cytopathic and antigenic simian immunodeficiency virus variants influence AIDS progression
Article Abstract:
Emerging cytopathic and antigenic simian immunodeficiency virus variants have been found to influence AIDS progression. Macaques were infected with cloned simian immunodeficiency viruses representing prototype variants from early-, intermediate- and late-stage infection having biological characteristics typical of viruses found at similar stages of HIV infection in humans.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 1999
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HIV swiftly guts the immune system
Article Abstract:
A research on AIDS confirmed that the gut and other mucosal tissues is the major site of HIV infection and CD4+T cell loss rather than the blood. It is found that simian immunodeficiency virus (SIV) rapidly and selectively infects and destroys memory CD4+T cells with in days of infection.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2005
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