Hypopituitarism after tuberculous meningitis in childhood
Hypopituitarism appears to develop in a significant percentage of people who had tuberculous meningitis as children, and signs of the disorder should be closely monitored because early treatment can greatly improve it. Hypopituitarism, which is a deficiency in hormones caused by abnormalities in the hypothalamus or pituitary gland, can result in short stature, sexual immaturity and diabetes. Of 49 people who had tuberculous meningitis before age 20, 10 were found to have abnormal pituitary function. Seven had growth hormone deficiency, four of whom also had gonadotropin hormone deficiency. One had gonadotropin hormone deficiency alone, one had corticotropin hormone deficiency and one had an excess of the hormone prolactin. Magnetic resonance imaging revealed that five of the 10 patients had structural abnormalities of the hypothalamus, the pituitary gland or the pituitary stalk.
Publication Name: Annals of Internal Medicine
Adult health problems linked to traumatic childhood experiences
The Adverse Childhood Experiences study has established a link between adult disability and death and adverse emotional childhood experiences. Conducted by the Kaiser Permanente Medical Care Program, Centers for Disease Control and Prevention, Emory University and the University of Arizona Health Sciences Center, the study has suggested that childhood abuse and household dysfunction may lead some to adopt health risk behaviors as coping devices, including cigarette smoking, obesity, physical inactivity, alcoholism, drug abuse, suicide attempts and sexual promiscuity.
Publication Name: World Disease Weekly Plus
- Abstracts: Expanding priorities - Confronting chronic disease in countries with low income. Alzheimer's disease and Parkinson's disease
- Abstracts: Keeping foods of animal origin safe. Resurgence of communicable diseases in Europe. Emerging foodborne diseases
- Abstracts: Factors affecting outcome in meningococcal infections. Fifth disease and other parvovirus B19 infections. Factors influencing postoperative recurrence of Crohn's disease in childhood
- Abstracts: Medical education. Continuing Medical Education for Ophthalmologists. General public education
- Abstracts: Controlling Rh haemolytic disease of the newborn in India. Immunoprophylaxis for rhesus disease - expensive but worth it?