Delayed hypotension and subendocardial injury after repeated umbilical cord occlusion in near-term fetal lambs

Article Abstract:

Fetal asphyxia can damage the heart, according to a study in sheep. Asphyxia occurs when the fetus is deprived of oxygen. Heart damage can occur even if oxygen levels return to normal.

Author: Gunn, Alistair J., Maxwell, Linda, Haan, Harmen H. de, Bennet, Laura, Williams, Christopher E., Gluckman, Peter D., Gunn, Tania R.
Injuries, Heart

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ST waveform changes during repeated umbilical cord occlusions in near-term fetal sheep

Article Abstract:

Changes in the ST segment on the electrocardiogram of a fetus may indicate that the fetus is not receiving enough oxygen. This was the conclusion of a study of pregnant sheep.

Author: Gunn, Alistair J., Bennet, Laura, Williams, Christopher E., Westgate, Jenny A., Brabyn, Christine
Diagnosis, Fetal heart rate monitoring, Electronic fetal monitoring, Fetal anoxia

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Fetal heart rate changes do not reflect cardiovascular deterioration during brief repeated umbilical cord occlusions in near-term fetal lambs

Article Abstract:

The circulation and oxygenation of fetuses may be impaired after brief occlusions of the umbilical cord, even though the pattern of fetal heart rate response may remain stable. Such a finding may explain why fetal heart rate monitoring does not clearly identify fetuses with deteriorating circulation and oxygen delivery. Twenty-one fetal lambs were used to test the effect of brief periods of asphyxiation on heart rate response. The response pattern of fetal heart rate decelerations remained stable as periods of asphyxiation increased. Low fetal blood pressure was the first sign of compromise.

Author: Gunn, Alistair J., Gluckman, Peter D., De Haan, Harmen H.
Causes of, Fetal heart rate, Hypotension

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Subjects list: Physiological aspects, Asphyxia
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