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Health and functional status of long-term survivors of bone marrow transplantation

Article Abstract:

Most people who live beyond five years after a bone marrow transplant lead fully functioning and healthy lives. Quality of life characteristics, the presence of new or returning disease, and death rates were evaluated among 798 adult and child patients who had survived more than five years after a bone marrow transplant. Eighty-nine percent of the patients were back at school or work and 93% were healthy. Most of the 55 people who died after five years died from disease associated with transplant rejection, cancer, returning disease, or AIDS.

Health aspects, Transplantation of organs, tissues, etc., Organ transplantation, Tissue transplantation, Transplantation

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Malignant Neoplasms in Long-Term Survivors of Bone Marrow Transplantation

Article Abstract:

Long-term immunosuppression increases the risk of cancer in people who receive bone marrow transplants. These patients must take immunosuppressive drugs to keep their immune system from rejecting the transplant. In a study of 1,036 people who received a bone marrow transplant, 3.5% had developed a new cancer 10 years later and 13% had developed one 15 years after the transplant. Use of cyclosporine to treat graft rejection was a significant risk factor for the development of a new cancer.

Complications and side effects, Risk factors, Diseases, Cancer

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Effectiveness of Immunosuppressive Therapy in Older Patients with Aplastic Anemia

Article Abstract:

Immunosuppressive therapy is effective in the treatment of aplastic anemia in the elderly. Aplastic anemia is a lack of blood cells, increasing the risk of infection and bleeding. Researchers studied 810 patients with the disease and found that older patients were more likely to die. The rates of treatment response, relapse, and complications were similar across age groups, with 62% of patients responding to therapy.

United States, Care and treatment, Aged, Elderly, Evaluation, Drug therapy, Aplastic anemia

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