How neutrophils recognize bacteria and move toward infection

Article Abstract:

Research presented concerns the role of protein CD38 in mediating calcium signals within neutrophils, which subsequently directs their migration toward lung tissue invaded by the pneumococcus bacteria that causes pneumonia. Topics addressed include immune system response to bacterial infection and the cyclic adenosine diphosphoribose and intracellular calcium (cADPE/Ca++) signaling process.

Author: Normark, Staffan, Normark, Birgitta Henriques, Hornef, Mathias
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2001
Physiological aspects, Cellular control mechanisms, Cell regulation, Calcium in the body, Calcium (Nutrient), Streptococcus pneumoniae

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Painful stimulation suppresses joint inflammation by inducing shedding of L-selectin from neutrophils

Article Abstract:

One of the ways the body regulates inflammation is by shedding L-selectin from the surface of neutrophils. L-selectin allows the neutrophil to bind to sites of injury and infection. The loss of L-selectin inhibits this response and might be useful in treating inflammatory conditions.

Author: Levine, Jon D., Rosen, Steven D., Strausbaugh, Holly J., Green, Paul G., Lo, Ernest, Tangemann, Kirsten, Reichling, David B.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 1999
Prevention, Inflammation, Cell adhesion molecules

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Staphylococcal protein A inflames the lungs

Article Abstract:

The severe and lethal infections in vulnerable individuals due to Stephylococcal aureus are analyzed. The major triggers for Staphylococcal pneumonia with a huge influx of inflammatory cells into the lungs are

Author: Normark, Staffan, Normak, Birgitta Henriques, Norrby-Teglund, Anna
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2004
Science & research, Staphylococcus aureus, Pneumonia, Bacterial pneumonia

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Subjects list: Research, Neutrophils
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