Hypertonic saline-dextran solutions for the prehospital management of traumatic hypotension
The effectiveness of giving accident victims a solution for pre-hospital treatment of life-threatening low blood pressure due to penetrating injuries was tested. The solution contained a higher salt concentration than the fluid that fills body cells (hypertonic) as well as dextran, a sugar. Forty-eight patients with penetrating injuries and a systolic (during contraction of the heart) blood pressure below 90 millimeters of mercury were given the hypertonic solution or a crystalloid plasmylate solution (a synthetic form of plasma, the clear fluid component of blood). There were no complications associated with administration of the hypertonic fluid, and execution of the procedure by paramedics was both safe and uniformly successful. The potential impact of this solution on emergency medical care and the favorable results of this study justify a larger evaluation of the effectiveness of this hypertonic solution in pre-hospital settings.
Publication Name: American Journal of Surgery
A new ACE inhibitor and two new angiotensin receptor blockers for hypertension
Three new drugs are available for treating hypertension: perindopril, telmisartan, and eprosartan. Perindopril, sold under the trade name Aceon, is an ACE inhibitor. ACE inhibitors block a specific enzyme that forms angiotensin II. However, other enzymes can also create angiotensin II. Consequently, angiotensin receptor blockers were created. These drugs block the binding of angiotensin II to its receptor. Telmisartan and eprosartan belong in this category of drugs. They are sold under the trade names Micardis and Teveten, respectively.
Publication Name: Medical Letter on Drugs and Therapeutics
Witnessed arrest, but not delayed bystander cardiopulmonary resuscitation improves prehospital cardiac arrest survival
A study is conducted on the effect of witnessing a cardiac arrest on 874 patients at emergency medical service area by instituting a bystander CPR (ByCPR) and early administration of sodium bicarbonate monitoring survival parameters. Results showed overall survival rate was more when witnessed but not necessarily when ByCPR was performed by layman.
Publication Name: Emergency Medicine Journal
- Abstracts: Impact of magnetic resonance imaging on the management of diabetic foot infections. Cardiac pathology in the hypertensive diabetic rat. Biventricular damage with right ventricular predominance
- Abstracts: Pleuropulmonary infections due to nontyphoid strains of Salmonella. Long-term suppression of Salmonella aortitis with an oral antibiotic
- Abstracts: Risk stratification according to the initial electrocardiogram in patients with suspected acute myocardial infarction
- Abstracts: Effect of transdermal nicotine delivery as an adjunct to low-intervention smoking cessation therapy: a randomized, placebo-controlled, double-blind study
- Abstracts: Primary pulmonary hypertension: its association with microangiopathic hemolytic anemia and thrombocytopenia. Unsuspected pulmonary tuberculosis in a community teaching hospital