Immunohistochemical evidence for the interaction between levator ani and pudendal motor neurons in the coordiantion of pelvic floor and visceral activity in the squirrel monkey

Article Abstract:

A study is conducted to characterize the spinal distribution of afferent and efferent pathways that innervate the levator ani (LA) muscle in the female squirrel monkey. The intriguing labeling of LA neural elements within a nucleus that innervates the external urethal and anal sphincters may represent a neuroanatomic substrate for physiologic integration of spinal and supraspinal inputs for the cooridanation of pelvic floor and visceral activity.

Author: Kuehl, Thomas J., Pierce, Lisa M., Reyes, Michelle, Thor, Karl B., Dolber, Paul C., Bremer, Ronald E., Coates, Kimberley W.
Usage, Motor neurons, Immunohistochemistry

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Innervation of the levator ani muscles in the female squirrel monkey

Article Abstract:

The anatomy of the muscles of the pelvic floor in the squirrel monkey appears to be similar to those in human women, according to a detailed anatomical study of 11 female monkeys. For this reason, the squirrel monkeys may make a good animal model to study disorders of the pelvic floor, including pelvic organ prolapse, urinary incontinence, and rectal incontinence.

Author: Kuehl, Thomas J., Pierce, Lisa M., Coates, Kimberly W., Reyes, Michelle, Thor, Karl B., Dolber, Paul C., Bremer, Ronald E.
Animal anatomy, Pelvis

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Evaluation of the aged female baboon as a model of pelvic organ prolapse and pelvic reconstructive surgery

Article Abstract:

The study examines the baboon as an animal model of pelvic organ prolapse (POP) by describing the pelvic floor anatomy and adapting human clinical assessment tools. As the pelvic anatomy is similar to the human female, the baboon may prove useful for evaluating surgical materials and for modeling pelvic floor reconstructive surgeries.

Author: Kuehl, Thomas J., Pierce, Lisa M., Coates, Kimberly W., Mattson, Julia A., Yandell, Paul M.
Care and treatment, Models, Baboons, Prolapse, Gynecology, Operative, Gynecological surgery

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Subjects list: Research, United States, Squirrel monkeys, Physiological aspects
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