Incidence of campylobacteriosis among patients with AIDS in Los Angeles County

Article Abstract:

Infection with the bacterial organism Campylobacter, campylobacteriosis, is the most common cause of acute bacterial diarrhea in the United States. The bacteria can be acquired by consumption of unpasteurized milk, undercooked chicken, untreated water, or by contact with cats. The incidence of campylobacteriosis among patients with AIDS has not been well studied. Using registries, the incidence and characteristics of campylobacteriosis among AIDS patients in Los Angeles County, California from 1983 to 1987 were analyzed. Campylobacteriosis was reported in 0.7 percent (29 out of 4,433) of the AIDS patients. This was 39 times the rate of that of the general population. The increased rate of infection in AIDS patients is a consequence of their compromised immune systems. Campylobacteriosis was more common in female than male AIDS patients. Infection occurred with seasonal variation, with a greater occurrence in July and November. The average survival time of AIDS patients who had campylobacteriosis was shorter than for AIDS patients without the disease (14 months compared with 21 months). However, other factors, such as other infections and/or treatment may also play a role in the decreased survival rates. AIDS patients who had campylobacteriosis had higher risk of the bacteria getting into the bloodstream, and a greater number required hospitalization than uninfected patients. Potential sources of campylobacteriosis should be identified and avoided by AIDS patients. (Consumer Summary produced by Reliance Medical Information, Inc.)

Health aspects, Diseases, Los Angeles, California, AIDS patients, Campylobacter infections, Campylobacteriosis

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Incidence of Epstein-Barr virus in AIDS-related lymphoma specimens

Article Abstract:

Epstein-Barr virus (EBV) may play an indirect role in the development of AIDS-related lymphomas (ARL). The role of EBV in the development of ARLs has ben controversial. Three different molecular biology techniques were used to detect EBV in paraffin embedded and frozen specimens from 30 patients with ARL. Seventeen patients had large-cell lymphoma, 11 had small non-cleaved cell lymphoma and two had Hodgkin's disease. EBV was detected by polymerase chain reaction (PCR) in 94% of the frozen specimens, compared with 17% of the paraffin embedded samples. In situ hybridization and antibody-based immunohistochemical staining detected EBV in less than 10% of the cells in 27 specimens.

Causes of, Lymphomas, Epstein-Barr virus

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