Inhaled and nasal glucocorticoids and the risks of ocular hypertension or open-angle glaucoma

Article Abstract:

Patients who take high doses of inhaled corticosteroids may have an increased risk of glaucoma or ocular hypertension. Inhaled corticosteroids are often used to treat asthma. Researchers compared the use of inhaled corticosteroids in 9,793 patients diagnosed with glaucoma or ocular hypertension and 38,325 people diagnosed with other eye diseases. Those who used high doses of inhaled corticosteroids for more than 3 months had a 44% increased risk of glaucoma or ocular hypertension. These patients should have regular eye examinations.

Health aspects, Corticosteroids, Adrenocortical hormones, Open-angle glaucoma, Intranasal medication, Nasal sprays

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Valvular heart disease and the use of dopamine agonists for Parkinson's disease

Article Abstract:

An echocardiographic prevalence study was performed in 155 patients taking dopamine agonists for Parkinson's disease and 90 control subjects. The findings reveal that the frequency of clinically important valve regurgitation was significantly increased in patients taking pergolide or cabergoline but not in patients taking non-ergot-derived dopamine agonists as compared with control subjects.

United States, Drug therapy, Parkinson's disease, Parkinson disease

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Dopamine agonists and the risk of cardiac-valve regurgitation

Article Abstract:

A cohort study was conducted with a nested case-control analysis to investigate the risk of newly diagnosed cardiac-valve regurgitation associated with the use of different dopamine agonists. The findings reveal that the use of the dopamine agonist's pergolide and cabergoline was associated with an increased risk of newly diagnosed cardiac-valve regurgitation.

Quebec

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