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Inhibin in normal and abnormal pregnancy: maternal serum concentration and partial characterization

Article Abstract:

A mother's inhibin concentrations are affected by fetal gender, gestational age and complications. Inhibin in the blood is a growth hormone associated with the development of the placenta and increase during pregnancy and decrease after birth. In a study, blood levels of inhibin were assayed in 33 mothers with abnormal pregnancy and matched with assays from 33 mothers with normal pregnancy. Inhibin levels were higher in abnormal, single baby pregnancies, in mothers with female babies and increased more rapidly as the pregnancy progressed in multiple pregnancies.

Author: Wortsman, Jacobo, Huffman, Dean G., Khalil, Ahlam, Kaufman, Robert C., Winters, Stephen J.
Publisher: Elsevier B.V.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1995
Measurement, Pregnancy, Complications of, Pregnancy complications

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Comparison of maternal serum total activin A and inhibin A in normal, preeclamptic, and nonproteinuric gestationally hypertensive pregnancies

Article Abstract:

Doctors might be able to measure blood levels of Activin A and inhibin A to determine whether a pregnant women has preeclampsia. Preeclampsia is a complication of pregnancy characterized by high blood pressure, swelling and mild kidney disease. Researchers measured blood levels of activin A and inhibin A in 60 pregnant women with preeclampsia and 60 pregnant women who did not have preeclampsia. Blood levels of both proteins were elevated in the women with preeclampsia compared to the other women.

Author: Canick, Jacob A., Silver, Helayne M., Hogan, Joseph, Lambert-Messerlian, Geralyn M., Star, Jami A.
Publisher: Elsevier B.V.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1999

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Second-trimester maternal serum inhibin A concentration as an early marker for preeclampsia

Article Abstract:

Elevated blood levels of inhibin A may predict which pregnant women will develop preeclampsia. Inhibin A is a naturally occurring growth factor in the human body.

Author: Harrington, Kevin, Aquilina, Joseph, Barnett, Adrian, Thompson, Olaleye
Publisher: Elsevier B.V.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1999
Statistical Data Included, Diagnosis

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Subjects list: Physiological aspects, Inhibin, Preeclampsia
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