Intracoronary injection of mononuclear bone marrow cells in acute myocardial infarction

Article Abstract:

A randomized, controlled trial, known as the Autologous Stem-Cell Transplantation in Acute Myocardial Infarction (ASTAMI) study, was conducted to investigate whether intracoronary injection of autologous mononuclear bone marrow (BMC) results in a clinically important improvement in left ventricular function as measured by the left ventricular ejection factor (LVEF). Results showed no effects of intracoronary injection of autologous mononuclear BMC on global left ventricular function.

New England States, Methods, Cells, Bone marrow cells, Cell transplantation

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Limiting myocardial damage during acute myocardial infarction by inhibiting C-reactive protein

Article Abstract:

A small molecule is designed that binds and inhibits human C-reactive protein (CRP) to reduce the size of myocardial infarctions. The availability of CRP inhibitor would facilitate experiments to determine the role of human CRP in normal biologic processes and disease states including atherogenesis, plaque instability, stroke, infection, inflammatory diseases and autoimmunity.

Science & research, Research, Stroke (Disease), Stroke, C-reactive protein

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Noninvasive assessment of myocardial viability

Article Abstract:

More research is needed to determine whether it is cost-effective to use MRI scans of the heart in heart attack patients to identify ares of tissue damage that is reversible. Studies have shown that patients who have areas of reversible damage have better outcomes after procedures to open up their blocked arteries.

Editorial, Usage, Heart, Magnetic resonance imaging

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