Abstracts » Health

Magnesium sulfate attenuates peroxide-induced vasoconstriction in the human placenta

Article Abstract:

Magnesium sulfate can prevent the constriction of arteries in the placenta, probably by blocking calcium. This was the conclusion of a study that exposed placentas taken soon after delivery to peroxide, magnesium sulfate and calcium chloride. Peroxide constricted the arteries in the placenta, but magnesium sulfate reduced arterial constriction. Calcium chloride restored arterial constriction. Magnesium sulfate also inhibited the production of a chemical called thromboxane, which is also involved in arterial constriction.

Prevention, Magnesium sulfate, Vasoconstriction

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Effect of an oxytocin receptor antagonist and rho kinase inhibitor on the [Ca(sup ++)]i sensitivity of human myometrium

Article Abstract:

A study to assess the possible mechanism and effect of oxytocin receptor on the sensitization of the contractile proteins to [Ca(sup ++)]i concluded that oxytocin independently regulates the duration of the period Ca(sup ++) signals and the sensitivity of the contractile machinery to Ca(sup ++). The latter is likely to be mediated by rho kinase, which is essential for the effective coupling of increases in [Ca(sup ++)]i to tension.

Science & research, Influence, Oxytocin

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The effects of placental extracts from normotensive and preeclamptic women on vasoconstriction and oxidative metabolism

Article Abstract:

Placental extracts from pregnant women who had preeclampsia during pregnancy increased oxygen consumption and blood vessel constriction in a carotid artery taken from a pig. This shows that some substance in the placenta may cause preeclampsia, which is a complication of pregnancy.

Preeclampsia

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