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Positive Results on Tests for Steatorrhea in Persons Consuming Olestra Potato Chips

Article Abstract:

Consumption of foods containing olestra may cause large amounts of fat to be excreted in fecal material. Olestra is a fat substitute. People who eat these foods could be mistakenly diagnosed with a gastrointestinal malabsorption syndrome. Researchers measured the amount of fat in fecal material from 10 healthy volunteers after they ate regular potato chips or potato chips containing olestra. When participants ate 40 grams of olestra per day, they excreted as much fat as patients with malabsorption syndrome.

Author: Balasekaran, Ranga, Porter, Jack L., Santa Ana, Carol A., Fordtran, John S.
Publisher: American College of Physicians
Publication Name: Annals of Internal Medicine
Subject: Health
ISSN: 0003-4819
Year: 2000
Diagnosis, Diagnostic errors, Olestra

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Malabsorption due to cholecystokinin deficiency in a patient with autoimmune polyglandular syndrome type I

Article Abstract:

Doctors describe a 46-year-old man with autoimmune pollyglandular syndrome type I who had intestinal malabsorption caused by a deficiency of cholecystokinin. Autoimmune pollyglandular syndrome is an autoimmune disorder that attacks endocrine glands. In this case, the cholecystokinin deficiency was caused by a lack of endocrine cells in the intestinal mucosa.

Author: Porter, Jack L., Santa Ana, Carol A., Fordtran, John S., Hogenhauer, Christoph, Meyer, Richard L., Netto, George J., Bell, Diana, Little, Katherine H., Ferries, Laura
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2001
Case studies, Autoimmune diseases, Endocrine gland diseases, Endocrine diseases

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Proton-pump inhibition of gastric chloride secretion in congenital chloridorrhea

Article Abstract:

The proton pump inhibitor omeprazole may be effective in treating congenital chloride diarrhea. This condition is characterized by abnormal secretion of chloride into the intestines, which causes chronic diarrhea. Researchers tested the anti-ulcer drug omeprazole in a patient with congenital chloride diarrhea. Omeprazole inhibits the secretion of chloride in the stomach and very effectively reduced the secretion of chloride in this patient. Omeprazole reduced the size and frequency of his bowel movements. He continued taking 20 milligrams twice a day and was able to return to work.

Author: Porter, Jack L., Santa Ana, Carol A., Fordtran, John S., Aichbichler, Berendt W., Zerr, Charles H.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1997
Health aspects, Drug therapy, Diarrhea, Stomach, Omeprazole, Chlorides, Gastric juice, Chlorides in the body

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Subjects list: Causes of, Physiological aspects, Malabsorption syndromes
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