Prepregnancy weight and pregnancy outcome
There appears to be an association between neural tube defects (NTD) in newborn infants and their mother's weight before pregnancy, but the cause is unknown. Two 1996 studies revealed that obese women had a greater risk of delivering a baby with a NTD. Obese women have a higher risk of other complications of pregnancy, including preeclampsia, urinary tract infections and cesarean delivery. Obese women are more likely to have diabetes and hypertension. Extremely thin women are also endangering their babies, mostly by increasing the risk of premature birth and growth retardation. The discovery that folic acid intake does not reduce the risk of NTD in babies of obese mothers is not surprising. Zinc supplementation and aspirin use in pregnant women have different effects depending on the woman's body mass index. The association between obesity and NTDs is alarming considering the fact that the incidence of obesity is rising in the US population.
Publication Name: JAMA, The Journal of the American Medical Association
Impact of maternal group B streptococcal screening on pediatric management in full-term newborns
The infants of pregnant women who receive testing and preventive treatment for group B streptococcus (GBS) may receive more intensive pediatric care even if they do not show symptoms of GBS. GBS is the biggest cause of infections of the blood in newborns, some of which may result in death. Researchers surveyed members of the American Academy of Pediatrics regarding their care of newborns according to the mother's GBS status. Pediatricians were more likely to test asymptomatic newborns and prescribe antibiotics when the mother was known to test positive for GBS and received antibiotics prenatally.
Publication Name: Archives of Pediatrics & Adolescent Medicine
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