Atovaquone/proguanil (Malarone) for malaria
The FDA has approved the drug combination atovaquone/proguanil for the prevention and treatment of malaria. Sold under the trade name Malarone, it inhibits the parasite's mitochondria and also blocks the enzyme dihydrofolate reductase.
Publication Name: Medical Letter on Drugs and Therapeutics
Mefloquine is used as malaria prophylaxis in areas where chloroquine is ineffective. It is considered to be appropriate for use by people with renal impairment and does not require dosage reduction.
Publication Name: Nursing Times
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