Metabolic issues associated with protease inhibitors

Article Abstract:

A brief discussion on the consequences and management of risk for cardiovascular disease (CVD) and type2 diabetes mellitus in persons with HIV infection is presented. Protease inhibitor (PI) plays an important role in the observed changes in the metabolic parameters during antiretroviral therapy (ART).

Author: Moyle, Graeme
Health aspects, Cardiovascular diseases, Risk factors, Type 2 diabetes, HIV patients, Clinical report

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Eradication of cryptosporidia and microsporidia following successful antiretroviral therapy

Article Abstract:

Highly active retroviral therapy (HAART) can eliminate cryptosporidia and microsporidia, which are two protozoal diseases that often affect HIV patients. Patients must be treated for six months to completely eradicate the organisms.

Author: Gazzard, Brian G., Miao, Yin M., Awad-El-Kariem, Fatih M., Franzen, Caspar, Ellis, David S., Muller, Andreas, Counihan, Helen M., Hayes, Peter J.
Cryptosporidiosis, Anti-HIV agents

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Comparison of virologic, immunologic, and clinical response to five different initial protease inhibitor-containing and nevirapine-containing regimens

Article Abstract:

The protease inhibitors indinavir and nelfinavir appear to be the most effective protease inhibitors, especially when combined with nevirapine. Saquinavir in hard gel format was the least effective protease inhibitor.

Author: Gazzard, Brian G., Moyle, Graeme, Esaterbrook, Philippa J., Newson, Roger, Ives, NAtalie, Pereira, Scott

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Subjects list: Protease inhibitors, Evaluation, HIV infection, Drug therapy, HIV infections
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