Nicotine Patch Therapy in 101 Adolescent Smokers: Efficacy, Withdrawal Symptom Relief, and Carbon Monoxide and Plasma Cotinine Levels
Nicotine patch therapy does not appear to be effective for teens who want to stop smoking. In a study of 101 teen smokers who received 6 weeks of nicotine patch therapy and follow-up visits every few months, only 5% had successfully quit smoking at 6 months. This abysmal failure rate was confirmed by testing blood samples for cotinine, a metabolite of nicotine. Although smoking rates decreased during the study, this was less apparent at the six-month follow-up.
Publication Name: Archives of Pediatrics & Adolescent Medicine
Transdermal nicotine for mildly to moderately active ulcerative colitis: a randomized, double-blind, placebo-controlled trial
Highly concentrated nicotine patches worn for one month appear to be effective in treating patients with moderate signs of ulcerative colitis. Signs of disease progress were evaluated among 64 patients with mild to moderately active ulcerative colitis who wore patches containing either highly concentrated nicotine or placebo for four weeks. Thirty-nine percent of the patients wearing nicotine patches showed signs of improvement compared to 9% of those wearing placebo patches. Reported side effects included nausea, skin reactions, and an inflamed pancreas.
Publication Name: Annals of Internal Medicine
Nicotine patch use in pregnant smokers: nicotine and cotinine levels and fetal effects
Nicotine replacement therapy does not appear to have significant adverse effects on the fetus. Therefore, it may be appropriate to offer pregnant smokers nicotine replacement therapy to prevent smoking-related pregnancy complications.
Publication Name: American Journal of Obstetrics and Gynecology
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