Limiting stroke-induced damaged by targeting an acid channel

Article Abstract:

The report by Xiong et al. points the way to a neuroprotective strategy for stroke, mainly to develop a small-molecule inhibitor of acid-sensing ion channel 1 (ASIC1) or its components. The context-dependent activation of ASIC1 with acidification makes this cation channel a particularly intriguing target for new stroke therapies.

United States, Care and treatment, Drug therapy, Stroke (Disease), Stroke

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Love at first smell- The 2004 Nobel Prize in physiology or medicine

Article Abstract:

Linda Buck and Richard Axel were awarded the 2004 Nobel Prize in Physiology or Medicine 'for their discoveries of odorant receptors and the organization of the olfactory system'. Buck and Axel in 1991 reported a large family of rat genes that, they hypothesized, encoded odorant receptors.

United Kingdom, Achievements and awards, Neurobiologists, Buck, Linda, Axel, Richard

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