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Pegylated interferon-alpha protects type 1 pneumocytes against SARS coronavirus infection in macaques

Article Abstract:

The primary cause of severe acute respiratory syndrome (SARS) is a newly discovered corona-virus. Also shown is that prophylactic treatment of SCV-infected macaques with the antiviral agent pegylated interferon-alpha (IFN-alpha) significantly reduces viral replication. Therefore pegylated IFN-alpha protects type 1 pneumocytes from SCV infection and should be considered a candidate drug for SARS therapy.

Author: Fouchier, Ron A.M., Haagmans, Bart L., Kuiken, Thijs, Martina Byron, E., Rimmelzwaan, Guus
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2004
Causes of, Severe acute respiratory syndrome, Antibiotic prophylaxis

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Antibiotics- An investment worth making?

Article Abstract:

The combination of significantly increased regulatory risk and shrinking margins make it tough for investors to continue investment in antibiotic research and development, due to which, venture capital investors are showing greater caution. A study explores the problems facing the field and discusses some ways of solving them.

Author: Christoffersen, Ralph E.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2007
Financial management, Company investment, Investments, Pharmaceutical research

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Identification of a new human coronavirus

Article Abstract:

A fourth human coronavirus, HCOV-NL63, is identified after screening individuals having respiratory illnesses. A detailed description of this HCOV-NL63 virus is presented.

Author: Hoek, Lia van der, Vermeulen-Oost, Wilma, Wolthers, Katja C., Kaandorp, Jos, Berkhout, Ben, Spaargaren, Joke, Dillen Pauline M.E. Wertheim-van, Berkhout, Ron J.M., Pyrc, Krzysztof, Jebbink Maarten F.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2004
Respiratory tract infections

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Subjects list: Research, United States, Antibiotics, Coronaviruses
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