Polymorphisms of the TAP1 and TAP2 transporter genes in Japanese SLE

Article Abstract:

There does not appear to be a correlation between various forms of a genetic sequence called transporter associated with antigen processing (TAP) and systemic lupus erythematosus (SLE) among Japanese patients. Blood samples from 52 Japanese patients with SLE and 95 healthy volunteers (control group) were genetically typed for forms of TAP1 and TAP2. The only TAP form present in a higher frequency among patients than the control group was TAP2H with 5.8% of the patients with SLE carrying it and 0% of the control group carrying it.

Author: Takeuchi, F., Nakano, K., Nabeta, H., Hong, G.H., Kuwata, S., Ito, K.
Publisher: British Medical Association
Publication Name: Annals of the Rheumatic Diseases
Subject: Health
ISSN: 0003-4967
Year: 1996
Japanese, Japanese (Asian people)

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA

The A-G polymorphism in exon 1 of the CTLA-4 gene is not associated with systemic lupus erythematosus

Article Abstract:

Variants of the cytotoxic T lymphocyte associated-4 (CTLA-4) gene do not appear to be relevant to the development of systemic lupus erythematosus, an autoimmune connective tissue disorder. Researchers analyzed the gene in 126 lupus patients and 363 healthy patients, but could find no association between the gene and the disease.

Author: Barnett, Anthony H., Heward, Joanne, Allahabadia, Amit, Franklyn, Jayne A., Gordon, Caroline, Gough, Stephen C.L.
Publisher: British Medical Association
Publication Name: Annals of the Rheumatic Diseases
Subject: Health
ISSN: 0003-4967
Year: 1999
United Kingdom, Genetic polymorphisms

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA

Association between interleukin 6 gene polymorphisms and Behcet's disease in Korean people

Article Abstract:

Study results on the relation between interleukin 6 gene polymorphisms in Korean patients with Behcet's disease are presented.

Author: Chang, H.K., Jang, W.C., Park, S.B., Han, S.M., Nam, Y.H., Lee, S.S., Kim, J.U., Lee, H.S.
Publisher: British Medical Association
Publication Name: Annals of the Rheumatic Diseases
Subject: Health
ISSN: 0003-4967
Year: 2005
South Korea, Science & research, Research, Diagnosis, Behcet's disease, Behcet's syndrome, Interleukin-6

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA


Subjects list: Health aspects, Genetic aspects, Systemic lupus erythematosus
This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.