The use of estrogens and progestins and the risk of breast cancer in postmenopausal women
Article Abstract:
The addition of progestins to estrogen replacement therapy does not appear to lower the risk of breast cancer in postmenopausal women. The Nurses' Health Study followed 121,700 registered nurses from 1976 to 1992. The nurses received questionnaires every two years asking about menopause, hormone replacement therapy use, and breast cancer diagnosis. The percentage of the nurses taking progestin alone or with estrogen rose from 18% in 1986 to 30% in 1990. Researchers found that progestins added to estrogen therapy did not decrease the incidence of breast cancer. Furthermore, estrogen by itself or with progestin and progestins alone seem to increase the risk of breast cancer. Women should weigh the risk of breast cancer when deciding on long-term hormone replacement therapy.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1995
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Fruit and Vegetable Intake in Relation to Risk of Ischemic Stroke
Article Abstract:
Eating fruits and vegetables may lower the risk of stroke. Researchers analyzed the link diet and stroke in 75,596 women in the Nurses' Health Study and 38,683 men in the Health Professionals' Follow-up Study. Over an 8- to 14-year period, 366 women and 204 men had a stroke. Those who ate the most fruits and vegetables every day had a 30% lower risk of having a stroke than those who ate the least. Green leafy vegetables and cruciferous vegetables such as broccoli, cabbage, cauliflower, and brussel sprouts were the most beneficial, as were citrus fruits and citrus fruit juice.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1999
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- Abstracts: Postmenopausal estrogen therapy and cardiovascular disease: ten-year follow-up from the Nurse's Health Study
- Abstracts: Past use of oral contraceptives and cardiovascular disease: a meta-analysis in the context of the Nurse's Health Study
- Abstracts: Implications of obesity for cardiovascular disease in blacks: the CARDIA and ARIC studies. Association of hormone-replacement therapy with various cardiovascular risk factors in postmenopausal women
- Abstracts: The impact of obesity on left ventricular mass and geometry: the Framingham Heart Study. part 2 Prognosis after first myocardial infarction: comparison of Q-wave and non-Q-wave myocardial infarction in the Framingham Heart Study
- Abstracts: Racial variations in the prevalence of open-angle glaucoma: the Baltimore Eye Survey. Health and mental health problems of homeless men and women in Baltimore
