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The analysis of costimulatory receptor signaling cascades in normal T lymphocytes using in vitro gene transfer and reporter gene analysis

Article Abstract:

Research has been conducted on the T lymphocytes. The introduction of DNA into non-dividing normal human and murine T lymphocytes while maintaining high cell viability has been carried out via the transient transfection procedure and the results are presented.

Author: Bell, Michael P., Huntoon, Catherine J., Graham, Daniel, McKean, David J.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2001
Statistical Data Included, Research, DNA, T cells, Genetic research

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A dominant-negative therapy for anthrax

Article Abstract:

The author discusses anthrax, a disease caused by the Gram-positive bacterium Bacillus anthracis toxins. The point of interest includes the oligomeric structure of the anthrax toxin that can be exploited as a therapeutic or preventative vaccine.

Author: Leppla, Stephen H.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2001
Health aspects, Causes of, Physiological aspects, Vaccines, Toxins, Gram-positive bacteria, Anthrax, Oligomers

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Subjects list: United States, Analysis, Medical research
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