Predictive value of early virologic response in HIV/hepatitis C virus-coinfected patients treated with an interferon-based regimen plus ribavirin

Article Abstract:

A study was conducted to assess the utility of an early virologic response (EVR) to predict a sustained virologic response (SVR) to hepatitis C virus (HCV) therapy in a group of HIV/HCV-coinfected patients. The findings reveal that the rules of reduction of 2 log of the viral load at week 12 of HCV therapy in coinfected patients have the same value as those in monoinfected patients and high positive predictive value (PPV) provides a goal to motivate adherence during the therapy and stimulates patients to continue the treatment.

Diagnosis, Hepatitis C virus

---

Evolution of HIV resistance mutations in patients maintained on a stable treatment regimen after virologic failure

Article Abstract:

A study was conducted to compare the rate of emergence of thymidine analogue mutations (TAMs) and major protease inhibitor mutations in adherent patients who remained on stable treatment with a thymidine analogue and/or protease inhibitor after the onset of virologic failure. It is concluded that major protease inhibitor mutations arose more frequently and rapidly than did TAMs in patients with sustained virologic failure who received lamivudine

Usage, Gene mutations, Gene mutation, Protease inhibitors

---

Cervical shedding of HIV-1 RNA among women with low levels of viremia while receiving highly active antiretroviral therapy

Article Abstract:

A cohort of women is investigated to identify the factors associated with cervical HIV-1 RNA shedding in women with low and undetectable plasma HIV-1 RNA. The analysis has described the risks for genital HIV-1 RNA shedding in women with low/undetectable plasma virus.

Women, Women's health, RNA

Similar abstracts:

• Abstracts: Selection and persistence of viral resistance in HIV-infected children after exposure to single-dose nevirapine
• Abstracts: Value and limitations of chest pain history in the evaluation of patients with suspected acute coronary syndromes
• Abstracts: Neuroactive antiretroviral drugs do not influence neurocognitive performance in less advanced HIV-infected patients responding to highly active antiretroviral therapy
• Abstracts: Determinants of survival without antiretroviral therapy after infancy in HIV-1-infected Zambian children in the CHAP trial
• Abstracts: The new era of medical imaging - Progress and pitfalls. Communication between physicians and patients in the era of E-medicine

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.