The use of oral mexiletine for the treatment of pain after peripheral nerve injury

Article Abstract:

Mexiletine reduced pain scores by 30% in patients with pain from peripheral nerve dysfunction or injury. The pain had not been controlled by other medications. Patients were asked to rate their pain on a scale of one to 10, with 10 being the most intense. One group was given 750 mg per day. The other received their usual pain medication. After one moth, the groups were reversed. Median pain scores were seven prior to receiving mexiletine and in the placebo group. After mexiletine treatment, pain was rated at four. Patients experienced only mild side effects from this oral antiarrhythmic drug.

Health aspects, Injuries, Drug therapy, Pain, Nerves, Peripheral, Peripheral nerves, Mexiletine

---

Clinical manifestations of sarin nerve gas exposure

Article Abstract:

The symptoms, diagnosis, and treatment of sarin poisoning are reviewed. Sarin was originally developed as an insecticide but was quickly adopted as a chemical weapon. It was used during the Iran-Iraq war in the 1980s and in the 1994-1995 Aum Shinrikyo attacks in Japan. Sarin is an acetylcholinesterase inhibitor.

Care and treatment, Diagnosis, Complications and side effects, Poisoning, Nerve gas, Nerve agents

---

Similar abstracts:

• Abstracts: Progress in medical defense against nerve agents. Neural Mechanisms of Anhedonia in Schizophrenia: A PET Study of Response to Unpleasant and Pleasant Odors
• Abstracts: Treatment of nonseptic olecranon bursitis. The use of porcine factor VIII concentrate (Hyate: C) in the treatment of patients with inhibitor antibodies to factor VIII: a multicenter US experiment
• Abstracts: Incidence, risk factors, and clinical course of acute renal insufficiency after cardiac catheterization in patients 70 years of age or older: a prospective study
• Abstracts: Epidural anesthesia as an adjunct to retroperitoneal aortic surgery. Staged repair of interrupted aortic arch with ventricular septal defect compared with primary repair in infancy
• Abstracts: An experience with upper-extremity vascular trauma. Utility of the cervical spine radiograph in pediatric trauma

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.