HIV-1 incidence among male workers at a sugar estate in rural Malawi

Article Abstract:

About 24% of the men working at a sugar plantation in Malawi, Africa, were infected with HIV in 1994. However, the rate subsequently dropped to an average of 4% of the men becoming infected every year.

Malawi, Diseases, Agricultural laborers

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Quantitative analysis of HIV-1 variants with the K103N resistance mutation after single-dose nevirapine in women with HIV-1 subtypes A, C, and D

Article Abstract:

A sensitive point mutation assay, LigAmp, is used to detect and quantify K103N-containing variants in African women who received single-dose nevirapine (NVP) to prevent mother-to-child HIV-1 transmission. The results have shown that after administration of single-dose NVP, K103N is detected more frequently and at higher levels in women with subtypes C and D than A.

Science & research, Research, Gene mutations, Gene mutation, Drug therapy, HIV (Viruses), HIV, Genetic aspects, Disease transmission, Dosage and administration, Nevirapine

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HIV infection and disturbances of vaginal flora during pregnancy

Article Abstract:

Bacterial vaginosis may predispose many African women to HIV infection. Bacterial vaginosis is an inflammation of the vagina caused by bacterial infection. In a study of 9,148 women who were tested in 1993, 30% were HIV-positive. Thirty percent of the women had bacterial vaginosis and 59% had abnormal amounts of normal bacteria in the vagina. These women were two to three times more likely to be HIV-positive. Many normal bacteria in the vagina protect against infection, but if the levels of these bacteria change, that protective effect would be lost.

Complications and side effects, Physiological aspects, Vaginosis, Vagina

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