Quinolone-resistant Campylobacter jejuni infections in Minnesota, 1992-1998

Article Abstract:

An increase in the incidence of quinolone-resistant Campylobacter jejuni infections in humans between 1992 and 1998 appears to be linked to the use of quinolone antibiotics in food animals. Researchers tested 4,953 isolates of the bacterium Campylobacter jejuni that were collected from Minnesota patients between 1992 and 1998. The percentage of isolates that were resistant to quinolone antibiotics increased from 1.3% in 1992 to 10% in 1998. Quinoline use by patients could only account for 15% of the cases between 1996 and 1998. Quinolones were licensed for use in poultry in the US in 1995 but this use was banned by the FDA in 1997.

Author: Osterholm, Michael T., Bender, Jeffrey B., Hedberg, Craig W., Besser, John M., Wicklund, Julie H., Smith, Kirk E., Moore, Kristine A., Leano, Fe T., Johnson, Brian P.
Health aspects, Causes of, Campylobacter, Antibiotics in animal nutrition, Animal nutrition, Veterinary antibiotics

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Multidrug-resistant Salmonella enterica serotype typhimurium associated with pet rodents

Article Abstract:

An outbreak of multidrug-resistant Salmonella enterica serotype Typhimurium infections associated with commercially distributed pet rodents are reported. The findings suggest that the routine delivery of nontherapeutic antimicrobials in food or water probably contributed to increased salmonella infection and shedding, facilitating increased transmission among animals and from animals to their human caretakers.

Author: Braden, Christopher R., Smith, Kirk E., Swanson, Stephen J., Snider, Cynthia, Boxrud, David, Wunschmann, Arno, Rudroff, Jo Ann, Lockett, Jana
United States, Science & research, Research, Salmonella enteritidis

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Use of molecular subtyping in surveillance for Salmonella enterica serotype typhimurium

Article Abstract:

Pulsed-field gel electrophoresis can be used to detect outbreaks of Salmonella enterica serotype typhimurium and to determine whether the bacterial strain is resistant to antibiotics. This species of Salmonella is the most common species isolated from humans and animals in the US.

Author: Osterholm, Michael T., Bender, Jeffrey B., Hedberg, Craig W., Boxrud, David J., Besser, John M., Wicklund, Julie H., Smith, Kirk E.
Usage, Identification and classification, Gel electrophoresis, Salmonella typhimurium

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Subjects list: Drug resistance in microorganisms, Microbial drug resistance
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